Electrochemical Regulation of the Cyanobacterial Circadian Oscillation
In-vivo monitoring of chlorophyll fluorescence revealed that the redox state of plastoquionone pool could be controlled by EC-EET with simply changing the electrode potential in the presence of biocompatible electron mediators. As a result, the endogenous circadian clock of S. elongatuscells was successfully entrained through periodically modulated EC-EET by emulating the natural light-and-dark cycle, even under constant illumination conditions. This represents the first example of regulating the biological oscillation via intracellular redox state by electrochemical technique.
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