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Glassy Carbon Electrodes Sequentially Modified by Thiol-Capped Gold Nanoparticles and Dendrimers for Detecting Uric Acid in Human Serum

Tuesday, 7 October 2014: 08:50
Expo Center, 1st Floor, Universal 11 (Moon Palace Resort)
A. S. Ramírez-Segovia (Universidad de Guanajuato), J. A. Banda-Alemán (Centro de Investigación y Desarrollo Tecnológico en Electroquímica SC), S. Gutiérrez-Granados (Universidad de Guanajuato), L. A. Godínez (Centro de Investigación y Desarrollo Tecnológico en Electroquímica SC), E. Bustos (Centro de Investigación y Desarrollo Tecnológico en Electroquímica S. C.), and J. Manríquez (Centro de Investigación y Desarrollo Tecnológico en Electroquímica SC)
Glassy carbon electrodes (GCE) were sequentially modified by thiol-capped gold nanoparticles (AuNp@thiol) and dendrimers (GCE/AuNp@thiol/dendrimer), in order to explore their capabilities as electrochemical detectors of UA in human serum samples at pH 2. The results showed that concentrations of UA detected by amperometry with GCE/AuNp@thiol/dendrimer were comparable to those concentrations obtained using the uricase-based enzymatic-colorimetric method.
See more of: Chemically Modified Electrodes III
See more of: H2: Chemically Modified Electrodes
See more of: Physical and Analytical Electrochemistry, Electrocatalysis, and Photoelectrochemistry
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