Advances in Voltammetric Sensors Using Combinations of Phthalocyanines with Nanoparticles and/or Biomolecules in LB and LbL Films
In this work combinations of phthalocyanines with nanoparticles and/or biomolecules in LB and LbL films have been developed and their structures have been analyzed. The films have been used as voltammetric sensors for the detection of compounds of interest in the food industry (i.e. phenols or organic acids). The role of the molecular interactions in the electrocatalytic properties or as biomimetic systems to immobilize biomolecules has been studied and the existence of synergistic effects has been evidenced. For instance, the combination of phthalocyanines with gold nanoparticles in LB films produced an increase in the sensitivity towards phenols and detection limits of 10-7 mol.L-1 were attained. Similar detection limits could be obtained by combining phthalocyanines with silver nanoparticles in LbL films. LB and LbL films combining phthalocyanines and amphiphilic molecules provided biomimetic environments where enzymes could preserve their functionality. Detection limits as low as 10-8 mol.L-1 towards phenols were attained.
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2F. J. Pavinatto, E. G. R. Fernandez, P. Alessio J..C. Constantino, J. A. de Saja, V. Zucolotto,d O. N. Oliveira Jr. C. Apetrei, M. L. Rodriguez-MendezOptimized architecture for Tyrosinase-containing Langmuir-Blodgett films to detect pyrogallol J. Materials Chemistry 21, 4995-5003 2011