Two graphene oxide (GO) materials with different layer size and proportion of functional groups in the basal planes (hydroxyl and epoxy) and in the edges (carbonyl and carboxyl) were used to modify the surface of commercially available screen printed electrodes. Cyclic voltammetry in 0.1 M KNO₃ was evaluated as an easy to use electrochemical methodology to reduce GO attached to the surface of screen-printed electrodes (SPEs). A cathodic peak related to the reduction of GO was identified, and the peak potential was correlated to the difficulty to reduce GO to Electrochemically Reduced Graphene Oxide (ERGO) depending on the functional groups present in the basal plane and in the edges of the original GO monolayers. Time resolved UV-VIS spectroelectrochemistry is used for the very first time as an ‘in situ’ characterization technique for real time monitoring the electrochemical reduction of graphene oxide. Raman spectroelectrochemistry is used for the first time in combination with miniaturised screen printed electrodes as an ‘in situ’ characterization technique to follow the reduction too.