In-situ characterization of electrode material under electrochemical reaction provides the unique opportunity to understand the material structure evolution under operation condition, which gives fundamental understandings of the material property and its relation to battery performance. By taking advantages of the state-of-art synchrotron X-ray techniques, it is highly accessible to investigate the chemical information and structural information with high spatial resolution and sensitivity when a suitable electrochemical cell is designed. In this work, we proposed a cell design that is capable to do 3D tomography, X-ray absorption spectra (e.g. XANES and EXAFS), and powder or single crystal diffraction under electrochemical reaction. Specifically, we will take the advantages of using Hard X-Ray Nanoprobe (HXN) with a spatial resolution of 15 nm that is recently commissioned at National Synchrotron Light Source-II to investigate the phase transition of LiFePO₄ and stress-strain analysis of other electrode materials through nanodiffraction.