Metal-organic frameworks (MOFs), such as zeolitic imidazolate framework-8 (ZIF-8), are recently used as carrier for catalysts of fuel cell systems to enhance the performance of catalysts, because of its high porosity structure and good electrical conductivity. Different synthesis methods and doping ways have an impact on the structure and characteristics of MOF doped with catalysts. A new type of MOF-based catalyst, which is synthesized by using an innovative method, high energy wet ball milling with zeolitic imidazolate framework-8 (ZIF-8) and nitrogen doped graphene (N-G) as raw materials, is investigated in this work. The main purpose of this paper is to study the characteristics of the new synthesized catalyst. The physical, chemical and structural characteristics of new MOF-based catalysts are analyzed through XPS, XRD, SEM and STEM-EDS. Moreover, this work is moving forward to find out the reaction mechanism of the new material synthesized by high energy wet ball milling.