Redox flow batteries (RFBs) are highly promising systems for large scale energy storage applications. Whereas most redox flow cells are based on metallic active species in aqueous media, there has been increasing interest in developing flow batteries based on solutions of redox active organic compounds in organic solvents in order to achieve higher energy density. Organic compounds with high redox potentials, which can be used for catholyte solutions, are available, but in order to take advantage of the high cell potentials that are possible in organic solvents, new organic anolyte materials with lower redox potentials are needed. This presentation will outline our assessment of bispyridinylidene-based anolytes. These compounds are low potential two-electron donors that can be modified to improve solubility, cell voltage, and to limit diffusion through the ion exchange membrane.