On June 7th of 2021, Secretary of Energy Granholm announced the Hydrogen Energy Earthshot (also know as the Hydrogen Shot) - an initiative to enable clean, low cost hydrogen within a decade. In addition, the Bipartisan Infrastructure Investment and Jobs Act (IIJA), signed by President Biden in November of 2021, includes $9.5 billion for clean hydrogen, which is made up of $8 billion for at least four regional clean hydrogen hubs and $1.5 billion for electrolysis and clean hydrogen manufacturing and recycling research, development, and demonstration. In addition to accelerating the research, development, demonstration, and deployment of clean hydrogen technologies (including foundational electrochemical process for production and utilization), these investments are expected to provide exciting regional opportunities for jobs creation, economic growth, energy independence, and environmental justice. The presentation will discuss key challenges and major opportunities being addressed through the U.S. Department of Energy’s Hydrogen Program (coordinated through its Hydrogen and Fuel Cell Technologies Office); with the aggressive but achievable ten-year goal put forward by the Hydrogen Shot of $1 for 1 kg of clean hydrogen.