Label-Free and Real-Time Photonic Sensors As Analytical Platforms for Environmental Monitoring of Pollutants and Medical Diagnosis
In this scenario, herein, we present some strategies for the production of label-free optical sensors based on NAA and NPSi. These strategies are based on the design and fabrication of specific nanoporous structures with enhanced optical response (e.g. microcavities, Fabry-Pérot structures, filters, etc.) and additional chemical functionalization of the inner surface to make these nanostructures sensitive to specific analytes. Figure 1 shows some scanning electron microscopy (SEM) images of NPSi and NAA structures. Furthermore, we analyze and discuss different detection techniques such as reflectometric interference spectroscopy, photoluminescent spectroscopy and test their performance in the detection of proteins and heavy metal ions. Finally, we discuss about the future and potential applications of these sensing platforms in areas such as environmental monitoring, biotechnology, medical diagnostics, drug screening, food safety and security.
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