Invited Presentation: Optical Detection of Individual Carbon Nanotubes: Nanotube Spectroscopy and Bioimaging

The optical microscopy of single molecules has recently been beneficial for many applications, in particular in biology. It allows a sub-wavelength localization of an isolated nano-object and a subtle probing of its spatio temporal nano-environment on cells as demonstrated on live neurons [1].

For many bio-applications, near infrared nanoprobes and/or more photostable nanoprobes than conventional fluorescent molecules or quantum dots are desirable. In this context, single walled carbon nanotube tubes are promising. A prerequisite is however to understand their optical properties in different environments including water/saline suspensions, to study their rheological/interaction behavior in crowded bio/cellular environments and further optimize their optical detection therein. Our current efforts toward these goals will be presented and comparisons with other near infrared probes will be performed [2].

 

References

[1] L. Groc, M. Lafourcade, M.Heine, M. Renner, V. Racine, J.-B. Sibarita, B. Lounis, D. Choquet & L. Cognet, J. Neuroscience, 27, 12433 (2007); M. Heine, L. Groc, R. Frischknecht, JC. Béïque, B. Lounis, G. Rumbaugh, RL. Huganir, L. Cognet, D. Choquet, Science, 320, 201 (2008).

[2] L. Cognet, D. Tsyboulski, J. Rocha, C. Doyle, J.M. Tour, R.B. Weisman, Science, 316 1465 (2007); N. Fakhri, FC. MacKintosh, B. Lounis, L. Cognet L, M. Pasquali, Science, 330 1804 (2010); S. Cambré, S.Santos, W. Wenseleers, R.T. Nugraha, R. Saito, L. Cognet and B. Lounis, ACS Nano 6, 2649 (2012); J.G. Duque, L. Oudjedi, J. J. Crochet, , S. Tretiak, B. Lounis, S.K Doorn and  L. Cognet JACS  135 (2013) 3379. E. Genin, Z. Gao, J. A. Varela, J. Daniel, T. Bsaibess, I. Gosse, L. Groc, L. Cognet, M. Blanchard-Desce Adv. Mat (2013) in press