Carbon Nanostructures Used for Screening in Biomedicine

Carbon nanotubes, carbon onions, and C₆₀ fullerenes were used as matrices for stochastic microsensors design. Maltodextrins, cyclodextrins and porphyrins were immobilized in the matrices to improve the stochastic behavior of the microsensors.

The “signatures” of HER-1, NSE, leptin, PAI-1 and hormones were recorded using this microsensors in stochastic mode. The “signatures” were used to identify these analytes on the diagrams obtained when whole blood was screened. Quantitative analysis was also performed using these microsensors. The results obtained using the proposed microsensors were correlating very well with those obtained using the standard methods used in clinical analysis.

Acknowledgements This work was supported by UEFISCDI PNII Program Ideas 2011-2014, Contract nr. 123/05.10.2011 and by ERC-like-3/07.2012 program.