Electrochemical Determination of Serotonin, in the Presence of Dopamine at a Carbon Paste Electrode Modified with Aunps-Bcd

In this work, we shown the electrochemical detection of serotonin (SR) in the presence of dopamine (DA), using a carbon paste electrode (CPE) modified with gold nanoparticles (NPs). The gold NPs were synthesized by the chemical method with b - cyclodextrin (AuNPs-b CD). Electrochemical treatment was applied to the electrode surface to distinguish between the oxidation signals of SR and DA. Electrochemical changes of the CPE surface were performed by forming multiple layers of AuNPs-b CD by cyclic voltammetry. The separation of oxidation peaks associated with the signals of SR and DA in acidic medium is shown in Figure 1. The results demonstrate that the film formation on the electrode inhibits the electrode surface passivation via the adsorbed species, which arise during the SR oxidation process. The electroanalytical determination was carried out using the electrochemical techniques: cyclic voltammetry (CV), differential pulse voltammetry (VDP) and square wave voltammetry (SWC).