MEMS Based Eit Technology for Non-Invasive Breast Cancer Diagsnostics

Non-invasive and radiation free medical imaging modalities for breast screening is increasingly in demand  as the health care industry is taking a paradigm shift from the traditional “treating the sick” to “keeping people healthy” model.   To address this need, we are developing a Nano Electrode Array based Electro Impedance Tomography (EIT) device.

The objective of this device is to become the leading solution for accurate and cost-effective non-invasive and radiation free early breast cancer detection medical imaging modality.This will be the  first medical imaging device to use nano-electrode array embedded in flexible textile as sensors (fabricated via MEMS processes) [1, 2, 3, 4, 5,6], scan across a wide frequency spectrum and allow scanning of both breasts simultaneously. In addition, it  is also the first device that simultaneously allows the scanning of lymph nodes located under the arm, a feature which is of value to oncologists tracking progression and treatment of cancers.

References:

1. D. Chung, A. Khosla, et al, “Flexible Ag/AgCl electrodes for applications in tissue Electrical Impedance Scanning (EIS)” Journal of The Electrochemical Society, 161 (2) B3071-B3076 (2014)
2. A. Khosla and B. L. Gray, “Preparation, characterization and micromolding of multi-walled carbon nanotube polydimethylsiloxane conducting nanocomposite polymer”; Materials Letters Volume 63, Issues 13-14, 31 May
   2009, Pages 1203-1206.
3. A. Khosla, B.L. Gray, “CONDUCTIVE ELASTOMERIC MATERIAL AND USES THEREFOR“ US Patent No. 61/113998- Issued.
4. A. Khosla, and B. L. Gray; “Micropatternable Multifunctional Nanocomposite Polymers for Flexible Soft NEMS and MEMS Applications” ECS Trans. 2012 volume 45, issue 3, 477-494.
5. Matthew Giassa, A. Khosla, B. L. Gray, Ash Parameswaran, Kirpal Kholi, Ramani Rameseshan. “Applications for Low Frequency Impedance Analysis Systems.”, Journal of Electronic Testing, Volume 26, Number 1, 139-144, 2010.
6. A. Khosla, and B. L. Gray; "Fabrication and properties of conductive micromoldable thermosetting polymer for electronic routing in highly flexible microfluidic systems", Proceedings of SPIE Vol. 7593, 759314 (2010)