Artificially Tailored Plasmonic Nanostructures for High-Performance Biosensing Devices

Rapid advances in nanoscience and nanotechnology have been driven by many novel experimentations, which have revolutionized nanostructure synthesis and fabrication for a variety of applications. Artificial and engineered nanoscopic structures, which interact with the electromagnetic field, extend the antenna concept into the optical wavelength for molecular detection applications. Currently, biosensors based on surface plasmon resonances (SPR) have become one of the most important tools for analyzing biomolecule interactions and detecting chemical and biological substances. They have been increasingly applied to life science and pharmaceutical research as well as some important areas such as medical diagnostics, environmental monitoring, food safety and security. Although there are numerous of development and studies on SPR biosensing systems and devices, it remains an ongoing challenge to design and fabricate the biosensors with high sensitivity, low cost, and the ability to realize lab-on-a-chip devices for point-of-care diagnostics. We will present project the hybrid nanostructures to expand the plasmonic sensing application and deepen the understanding of the mechanism in engineered photonic nanostructures but also aims for realizing a high sensitivity and low cost lab-on-a-chip biosensing device.