(Invited) New Electrochemiluminescent Materials for Bioanalysis

Monday, October 12, 2015: 14:45
Ellis West (Hyatt Regency)


Electrochemiluminescence (ECL), or electrogenerated chemiluminescence, is light-emitting phenomenon from electrochemical reactions. It has broad applications, such as immunoassays, DNA probe assays, aptasensors, biological study, drug screening, medicine determination, and light-emitting devices. Various ECL systems, such as ruthenium complex, luminol, semiconductor nanocrystals, graphene oxide, and nanoclusters, have been reported. Generally, ECL reactions involve in luminophores, coreactants, and electrode. Electrocatalysts and/or additives are also frequently used. The performance of ECL depends significantly on these materials used [1-2].

We have recently developed various materials to improve ECL performance, such as new coreactants, new luminophores, noble metal nanocrystals, silica nanomaterials, new electrodes. The possible mechanism for enhanced properties are discussed. The analytical applications of some materials were demonstrated. The use of these materials extends applications, improve ECL sensitivity and simplify detection. [3-7].



This project was supported by the National Natural Science Foundation of China (No. 21475123 and 21175126).


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   [2]  L. Zhang, W. X. Niu, G. B. Xu, Nano Today, 2012, 7, 586-605.

   [3]  X. Q. Liu, L. H. Shi, W. X. Niu, H. J. Li, G. B. Xu,  Angew. Chem. Int. Ed., 2007, 46, 421-424.

   [4]  W. J. Qi, Z. Y. Liu, J. P. Lai, W. Y. Gao, X. Y. Liu, M. Xu, G. B. Xu, Chem. Commun., 2014, 50, 8163-8166.

   [5]  L.Z. Hu, Z. Bian, H. J. Li, S. Han, Y. L. Yuan, L. X. Gao, G. B. Xu, Anal. Chem., 2009, 81, 9807-9811

   [6]  W. J. Qi, D. Wu, J. M. Zhao, Z. Y. Liu, W. Zhang, L. Zhang, G. B. Xu, Anal. Chem., 2013, 85, 3207.

   [7]  L. Zhang, W. X. Niu, W. Y. Gao, L. M. Qi, J. P. Lai, J. M. Zhao, G. B. Xu, ACS Nano 2014, 8, 5953–5958.