Fabrication of Shaped Controlled Cerium Oxide Nanomaterial for Highly Sensitive Enzymatic Glucose Biosensors

Wednesday, 4 October 2017: 09:00
Chesapeake J (Gaylord National Resort and Convention Center)
A. Fallatah, M. Almomtan, and S. Padalkar (Iowa State University)
Metal oxide semiconductors at the nanometric scale have attracted considerable attention in recent years. Cerium oxide (CeO2) is one such metal oxide semiconductor that has received significant attention due to its catalytic and free radical scavenging properties and finds applications in medicine, catalysis and sensing. Here CeO2 was prepared by electrodeposition technique on a fluorine doped tin oxide (FTO) substrate. For electrodeposition, cerium nitrate and dimethyl sulfoxide (DMSO) were used. Several CeO2 samples were prepared with varying amount of DMSO. The current density and temperature of deposition was 2 mA/cm² and 70°C respectively. The fabricated CeO2 samples were characterized by scanning electron microscopy (SEM), X-ray diffraction analysis (XRD) and UV-visible spectroscopy. Additionally, the CeO2 samples were tested for glucose sensing. The enzymatic glucose biosensor was prepared by immobilizing glucose oxidase (GOx) enzyme on the CeO2 samples. The amperometric current response of the glucose biosensor was recorded at every addition of glucose. Furthermore, electrochemical impedance spectroscopic (EIS) method was used to study the charge transfer in the fabricated biosensors. Finally, a comparison of different CeO2 biosensors was carried out.