Water disinfection is an important issue in the world. Nearly one billion of people are sick or dead on account of the water full with bacteria. To solve this problem, scientists have used semiconductor photocatalyst materials to replace those traditional sewage treatments which are high-cost and high-toxic. Photocatalyst materials will generate reactive oxygen species (ROS) with water under ultraviolet light. ROS can react with bacteria to achieve disinfection. However, the method is inefficient because ultraviolet light only accounts for 10% in solar energy. Therefore, we developed a new type of nanocatalyst-MoS₂, which can separate the electron-hole pairs to generate ROS under the visible light (about 50% solar energy) and force from the environment. Furthermore, we deposited gold nanoparticles on the surface of MoS₂ (Au@MoS₂), because gold nanoparticles will prolong the half time of combing electron-hole pairs to improve the efficiency of ROS generation. The disinfection efficiency of Au@MoS₂ can achieve 99.999% in 35 minutes. Compared with traditional photocatalyst materials, Au@MoS₂ is not only high efficiency but also unlimited by light, which make it more flexible in application. We believe the material has powerful potential for water disinfection in future due to multifunctional effect.