Transition metal oxides (TMOs), a typical materials family for electrodes of lithium-ion batteries (LIBs), have unstable capacity performance and lack of durability after combining with a flat current collector. Novel designs of both active materials and current collectors are necessary to eliminate those issues. In this work, a hierarchical micro-electrode for LIBs is successfully designed and fabricated. Anatase TiO₂ nanoparticles (diameter ~100 nm) are synthesized as the active materials. A porous Cu/Ni current collector with vertically-aligned Ni micro-channels supports TiO₂ active materials. Electrochemical characterizations illustrates that such electrode has enhanced capacity, stable rate performance, and durable lifespan. The maximum insertion coefficient for the Li ion intercalation reaction is as high as ~0.85, which is one of the greatest results for anatase LIB anodes. Furthermore, cross-sectional electron microscopic imaging along with X-ray energy dispersive spectroscopic elemental analysis confirmed the uniform spatial distribution of TiO₂ nanoparticles inside the Ni micro-channels. This distribution is maintained after numbers of cycles. A synergistic effect between nano-TiO₂ active material and porous Cu/Ni current collector is the main reason. The favorable properties of the Cu/Ni/TiO₂ anode are improved electrochemical reactivity, reduced lithium ion diffusion pathways, great specific surface area, effective buffering of volume changes of TiO₂ nanoparticles, and the optimal paths for chargers transport.