Our results highlight the differences in energy expenditure, oxidant generation, and EPBR operating conditions, as well as time needed for disinfection of blackwater as a function of packed bed electrode material and potentiometric treatment method. It is proposed that potentiodynamic treatment methods offer a more energy efficient and practical solution to treating blackwater than potentiostatic methods. Moreover, the benefits and drawbacks of using magneli-phase titanium oxide compared to common granularized carbon electrode materials are highlighted by correlating disinfection to energy expenditure and electrochemically generated oxidants. Reactive oxygen species, such as H₂O₂, and chlorine containing species, such as Cl₂, are quantified and correlated to the reduction of bacterial concentration for each electrode material and treatment method. Lastly, the effects of flow-rate, particle size, and blackwater composition are correlated to the optimal conditions for blackwater disinfection.