Recently, a tremendous upsurge in the research of Solid oxide fuel cells (SOFCs) has been documented due to cheap electricity production and without harming the environment. The development of efficient SOFCs requires more robust cathode for oxygen reduction. Until yet a copious amount of research has been done on varieties of materials including LSCF. In this work, Ruthenium is doped on the LSCF forming nanostructured Ru-LSCF with various Ru stoichiometric quantities. The Ru-LSCF catalyst is prepared via simplistic technique “Glycine combustion process”, producing evenly embedded Ru in LSCF perovskite materials leading to increased oxygen reduction reaction (ORR). The nanostructured Ru-LSCF cathode showed polarization resistance of approximately 0.031 Ωm² at 750 ⁰C. The peak powers of approximately 1760.5, 1480.1, 893.3 mW/cm² were recorded at 750, 700, and 650 ⁰C, respectively. Ru LSCF was quantitatively optimized for enhanced power production with high precision calculation. The results show that the Ru-LSCF optimum fabricated nanostructured cathode is promising catalyst for the reduction of oxygen at the cathode side for highly durable SOFCs.