In the low temperature fuel cells, it is of great importance to overcome a sluggish oxygen reduction reaction (ORR) by employing the highly effcient electrocatalysts. Due to high cost of the representative Pt based catalysts, it is highly required to develop non-precious metal or metal-free catalysts with high perforamance. In this sense, we developed N,P co-doped large pore sized ordered mesoporous carbons with high activity for ORR. A large pore sized N, P co-doped ordered mesoporous carbon with precisely controlled doping site position exhibited a remarkable on-set potential and produced 70% of the maximum power density obtained using Pt/C. We also developed an ordered mesoporous Fe/N/C catalyst for oxygen reduction reaction in fuel cells. By simple ‘one-pot’ process, we combined two necessary factors for the high performance of Fe/N/C catalyst in cathode of practical-level fuel cell. The ORR kinetic activity of the single Fe-Nx/C active site was increased by a new and versatilely applicable strategy. The incorporated electron withdrawing/donating functionalities changed the strength of the electronic effect, resulting in the change of ORR activity.