Electrocatalytic water splitting has been widely considered as a promising approach to produce clean hydrogen (H₂). The anodic half reaction of water splitting, O₂ evolution reaction (OER), is the kinetic bottleneck of the overall water splitting process while its product O₂ does not possess high market value. A novel strategy to replace OER with thermodynamically more favorable anodic reactions, such as the oxidative valorization of biomass-derived intermediates, represents an attractive approach, which not only reduces the overall voltage input but also produces two valuable products (H₂ and biomass products) at both electrodes. This talk will present our recent work in electrocatalytic biomass valorization integrated with H₂ production under ambient conditions. A series of biomass-derived intermediates, including 5-hdyroxymethylfurfural, furfural, furfuryl alcohol, and benzyl alcohol, were employed as representative organic substrates to be oxidized to value-added acids. 1^st-row transition metal-based electrocatalysts were developed to catalyze biomass oxidation and H₂ evolution. Results of long-term electrolysis demonstrated the bifunctionality of our electrocatalysts and nearly 100% Faradaic efficiencies for both H₂ production and biomass oxidation reactions.