A bipolar transistor’s operation can be categorized into four main modes as shown in the figure below based on the applied voltage to the base-emitter (VBE) and base-collector (VCB) junctions. Due to the asymmetrical junction engineering for vertical HBTs, the forward-active mode is usually the most optimized for device performance. Because it is the most utilized mode, it is also the most characterized for device reliability. In this paper, in addition to the mixed mode stress used to characterize SiGe bipolars, we will discuss some of the recent learning in SiGe HBT reliability in the other less-understood modes of operation. We begin with a brief overview of SiGe HBT reliability physics including hot carrier generation (Auger vs. Impact-Ionization), the temperature dependence of competing mechanisms and the physical damage responsible for electrical degradation. Using measurements and simulations, we discuss in detail the device degradation under off-state and saturation modes. We demonstrate how the hot carrier generation physics responsible for degradation in the forward-active mode is still applicable in the other regions of operation.