Electronic skin, which consists of various functional sensor arrays and can be applied to robot and wearable human-machine interfacing devices by mimicking the functions of human skin, requires flexibility, multifunctional mode, and high-sensitivity. Here, we developed a high-sensitivity, and high-reliability flexible dual-mode sensor with inkjet printable electrode material comprised of organic conductor-elastomer-metal nanoparticles. These involved vertically stacked sensors that utilize different sensing principles, thus enabling the realization of a dual-mode sensor with negligible interference. The pressure sensor has a high sensitivity over a wide-range (3Pa–5kPa), a fast response time (20ms), excellent reliability characteristics (100,000cycles) and a low operating voltage (0.5mV). The temperature sensor with a long bent organic conductor-metal line formed by the inkjet process can distinguish a temperature difference of 0.5 °C, and has a temperature sensitivity of 0.32% per °C. In addition, we demonstrated a dual-mode sensor with a 5×5 array structure that responded quickly and precisely in real-time, without interference effect. The low-resistivity and high-reliability flexible electrode and device structure used in this study are expected to be widely used in the future of soft touch displays, medical devices, and robotic applications.