Lithium-ion batteries have become the most widely used power source for the energy storage device , such as portableelectronic devices, long range electric vehicles andsmart grids. However, the energy densities of the state-of-the-art lithium-ionbatteries still cannot meet the increasing demand. As one of the most promising alternative electrochemical battery cathode materials, the lithium-rich layered oxides exhibit high specific capacities (230-250 mAh g−1) among all the cathode materials. The main drawback including voltage fade, large initial capacity loss, poor rate capability and limited cycle life hinder its practical applications. Approach strategies such as ionic doping and surface modification have been developed to improve the electrochemical performance and understand the origins of its high capacity, voltage decay and capacity fade in recent years. Herein, we successfully synthesized Mo-Doped Li2RuO3 through a solid-state reaction and systematically investigated the electrochemical performance of Li2Ru1-xMoxO3 (x = 0, 0.01, 0.02, 0.05) series. The results indicate this series materials show an enhanced electrochemical lithium reversibility than the pristine Li2RuO3 ， and Li2Ru0.98Mo0.02O3 exhibits the best performance in terms of specific capacity. Low content of Mo doping could realize an enhanced performance that originated mainly from the improved reversible anionic redox chemistry and charge transfer kinetics. It provide another choice for cathode materials for high performance LIBs.