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(Invited) Semiconductor-Based Biosensing Technology for Clinical Diagnosis

Monday, 29 May 2017: 08:00
Eglinton Winton (Hilton New Orleans Riverside)
T. Sakata (The University of Tokyo)
We are studying and developing biosensing techniques in order to analyze and monitor simply and easily biological phenomena such as DNA recognition events, antigen-antibody reaction and cell functions in vitro by use of functionalities of materials such as semiconductor. Particularly, we focus on a direct detection of ions or ionized molecules with charges, because most of biological phenomena are closely related to ionic or ionized molecular behaviors such as sodium or potassium ions through ion channel at cell membrane which are based on cell-cell communication for example, and DNA molecules also have intrinsic molecular charges based on phosphate groups. In order to detect directly ion or molecular charges, we would like to propose semiconductor-based biosensing devices based on the principle of field effect. In this talk, I will introduce some biosensing methods such as tear glucose sensing, cellular function sensing and so on with the semiconductor devices. In particular, I will point out the importance of three elements for biosensing such as detection device, signal transduction interface and biological target, as shown in image.