Flame spray pyrolysis process provides a cost effective way to make metal oxide powders. When the solvent is a green chemical, the process could become a sustainable manufacturing process for materials production. In this presentation, we will show that transition metal oxide powders can be produced in a flame spray process with a green solvent as the metal oxide precursor. It is also shown that complex transition metal oxide powders, such as Li(Ni_1/3Mn_1/3Co_1/3)O₂ and Li(Ni_0.8 Co_0.15 Al_0.05)O₂, can be produced in this process. These powders can be controlled to a certain degree in terms of powder sizes and morphology, to make them suitable for use in Li-ion batteries. Detailed results of the powder synthesis, characterization, and battery testing will be presented.